Hey, I’m Anh Tuan Pham.

A young man with dark hair, glasses, and a friendly smile, wearing a black suit, white shirt, and maroon tie, against a plain gray background.

Key Highlights:

  • Excelled in collaborating with multidisciplinary teams, led several successful discovery chemistry R&D programs:

    • Oversaw a lead optimization campaign for a small molecule immunomodulator against Aryl Hyrdocarbon Receptor (AhR). Delivered several highly active compounds with favorable ADME properties. Identified a prodrug as a development candidate.

    • Discovered novel highly selective organocatalysts based on peptide secondary structure and anion-π interactions for MAHT reaction.

  • Recognized for excellence with several scholarships and awards (e.g.: a scholarship to attend ResMed 2025, a travel award for the 2025 ACS Bridge Career Conference, and a Poster Prize at the First International Conference on Noncovalent Interactions - ICNI2019 (from Chemical Science, RSC)).

  • Recognized for expertise by invited roles as reviewers and editors for several scientific journals.

I am a chemist with experience in various domains of chemistry and biology. My expertise spans multistep organic synthesis, medicinal chemistry, supramolecular chemistry, and chemical biology.

Work with Me

My research experience

Harvard Medical School, Boston, MA

Center for Drug Discovery and Translational Research, Beth Israel Deaconess Medical Center

Instructor (Supervisor: Prof. Lijun Sun) - Nov.2025 - Present

Postdoctoral Research Fellow (Supervisor: Prof. Lijun Sun) - Jan. 2022 – Nov. 2025

Selvita, Krakow, Poland

Scientist - Oct. 2021- Jan. 2022

University of Geneva, Geneva, Switzerland

Department of Chemistry and Biochemistry

PhD candidate (Supervisor: Prof. Stefan Matile) - Sep. 2017- Sep. 2021

Saint-Petersburg State Chemical Pharmaceutical Academy, Saint-Petersburg, Russia

Department of Organic Chemistry and Department of Medicinal Chemistry

Research Student (Supervisor: Dr. Ovsyannikova L.N., Prof.  Lalaev B.Y., Prof. Kuklin B.N) - Sep. 2014 -Jul. 2017 

Several empty and partially filled clear glass beakers and test tubes on a lab table, with a pipette in one of the beakers.

Key skills

  • Synthetic chemistry

    Multistep Organic Synthesis (milligram to hundreds of grams): proficient in organometallic catalysis; air/moisture-sensitive chemistry; peptide solid phase synthesis; normal-phase and reverse-phase purification by flash chromatography and preparative HPLC; structural characterization by LC/MS, HRMS, NMR, IR; experienced with photoredox catalysis; electrochemistry. Reaction optimization: experienced with using high throughput screening platforms for reaction optimization. Reaction kinetic/mechanism studies.

  • Medicinal Chemistry

    Structure-based Drug Design; Ligand Drug Design; Lead optimization for desired potency, selectivity, ADME properties, in vivo efficacy, and safety profile. Experienced with small molecules (including molecular glues, prodrugs and antedrugs (soft drugs)) and bifunctional molecules such as PROTACs for targets in immuno-oncology.

  • Analytical Techniques and Data Analysis

    LC/MS, HPLC, UPLC, and LC-MS/MS for reaction monitoring, purification, and PK analyses; UV-Vis; Circular Dichroism

  • Software Proficiency

    Molecular docking and modeling: Docking (Glide, Autodock); Molecular Dynamic Simulation (Desmond); WaterMap; FEP+; High throughput virtual screening; lead optimization with Ligand Designer; AutoQSAR, DeepAutoQSAR (Machine learning for QSAR); basic DFT calculation (Maestro Materials Science), chemical database and literature searching using SciFinder and Reaxys; retrosynthesis synthesis software: SYNTHIATM, Manifold; scientific drawing and visualization using ChemDraw, MarvinSketch, PyMOL, ChimeraX, Biorender; NMR, LC-MS analysis using MestReNova, TopSpin, ChemStation, OpenLab CDS, ChromNav, Advion software suite; data analysis and plots using GraphPad Prism, RStudio.

  • ADME assays

    Solubility assays, metabolic stability assays (liver microsomes).

Education

University of Geneva, Geneva, Switzerland

PhD in Chemistry (Supervisor: Prof. Stefan Matile) -  Sep. 2017 – Sep.2021

Saint-Petersburg State Chemical Pharmaceutical Academy, Saint-Petersburg, Russia

Specialist degree in Pharmacy (equivalent to BS and MS combined degree) - Sep. 2012 – Jul. 2017

GPA: 5.0 (out of 5.0)

 

News

  • Nature conference "Cracking the Code: Nucleic Acid Medicines Coming of Age"

    Dec 08-10, 2025

    I'm attending the Nature conference "Cracking the Code: Nucleic Acid Medicines Coming of Age" at Harvard Medical School in Boston from Dec 08-10! Looking forward to exploring the developments and challenges in the rapidly evolving field of nucleic acid medicines.

    RSVP